Organization of the canine major histocompatibility complex: current perspectives
نویسندگان
چکیده
منابع مشابه
The major histocompatibility complex.
The major histocompatibility complex on the sixth chromosome controls expression of a complex series of cell surface antigens which comprise the human leukocyte antigen (HLA) system. These markers, beyond their importance in human organ transplantation, have been demonstrated to occur with an increased prevalence in certain disease states. The group of conditions showing the closest association...
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The major histocompatibility complex in swine (swine leucocyte antigen: SLA) is located on chromosome 7 with the class I and class III regions separated by the centromere from the class II region. The overall molecular organisation of the class I and III regions is well known, but further research is needed to establish that of the class II region. Approximately sixty genes have been characteri...
متن کاملThe major histocompatibility complex of ruminants.
Studies of the major histocompatibility complex (MHC) of cattle over the past twenty years have revealed a reasonably detailed picture of the genetic organisation and function of the genes within this genetic system. Serological and biochemical analysis of lymphocyte cell surface antigens provided the first evidence for highly polymorphic MHC genes in cattle and other ruminant species. The MHC ...
متن کاملEvolving views of the major histocompatibility complex.
T of parts of the MHC has grown substantially within the last year. HE MAJOR HISTOCOMPATIBILITY complex (MHC) is an extended cluster of genes that are remarkable for the number and importance of the immunological functions The MHC is of major biomedical interest because of its contribution to transplant rejection and to variation between they encode. Historically, interest in the MHC emanated f...
متن کاملMetal-derivatized Major Histocompatibility Complex
One of the prices we pay for our love of jewelry is allergic contact hypersensitivity to metal, an autoimmune condition that variably afflicts around 10% of all Caucasians (1). Contact hypersensitivity is a classic type IV DTH (delayed type hypersensitivity) response, involving primed T cells that are specific for metal modified antigens generated at a local site in the body (most commonly the ...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 1999
ISSN: 1471-8505
DOI: 10.1093/jhered/90.1.35